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Alex Yee teams up with Brownlee brothers as Olympics triathlon stars head all-star supertri lineup – Elite News

It’s been confirmed that the winners of no fewer than 11 Olympics medals in Paris – together with three golds – will race supertri League in 2024.

Alex Yee and Cassandre Beaugrand, who took the person golds, will compete for Brownlee Racing and Crown Racing respectively.

And Germany’s Blended Relay gold medallist Tim Hellwig is concerned in supertri for the primary time, together with his workforce to be revealed later this week.

As well as, American relay silver medallists Taylor Spivey and Seth Rider will compete, in addition to particular person silver winner Hayden Wilde.

Bronze medallists are Beth Potter, who bagged the identical honour in each the person and the relay, in addition to Léo Bergere, Georgia Taylor-Brown and Yee, who added a relay bronze to his particular person gold.

Don builds formidable Podium squad

The primary full workforce line-up to be revealed forward of the opening supertri occasion in Boston on Sunday August 18 is Podium Racing – and it options a mixture of French aptitude, younger expertise and uncooked energy.

Podium Racing was acquired by a gaggle of traders led by Podium Teaching Group supremo John Anthony and is managed by Tim Don.

Don has confirmed himself to be probably the most profitable supervisor in supertri, securing two of the three Groups titles to date – and he’s sticking to a profitable components.

From his victorious 2023 Eagles workforce he has retained Jeanne Lehair, an actual contender for the Ladies’s League, and Fanni Szalai, the 16-year-old he has mentored since she burst onto the worldwide stage with supertri.

He has added to {that a} former Eagle in Vittoria Lopes, whose gun swim energy offers them an actual edge, and nabbed French star Leonie Periault.

Within the males’s he has saved maintain of Bergere, the defending supertri champion and now Olympic bronze medallist, and Matt Hauser, the Australian who has been a supertri ever-present for the reason that begin, and is so determined to win a person title.

Wilde, Yee and Bergere will all be concerned in supertri once more [Photo credit: World Triathlon]

He has then made two shrewd strikes, recruiting World Champion Dorian Coninx – who works so nicely alongside compatriot Bergere – and Kenji Nener, who just isn’t solely vastly skilled in supertri however an actual workforce participant and workhorse.

The large query for Don is whether or not he can maintain the lads all completely satisfied, with three of the 4 positively having eyes on the Males’s League title?

The 2024 supertri schedule

Podium Racing will up in opposition to Brownlee Racing, Crown Racing and Stars & Stripes Racing for the five-stop supertri League:

  • August 18: supertri Boston
  • August 25: supertri Chicago
  • September 8: supertri London
  • October 6: supertri Toulouse
  • November 3: supertri NEOM
Beth Potter and Cassandre Beaugrand will lock horns once more at supertri [Photo credit: World Triathlon]

Moray pupils celebrate success with 2023/24 SQA exam results

Over 2,300 Moray secondary faculty pupils obtained their 2023/24 SQA examination outcomes this morning (Tuesday 6 August) by textual content, e-mail and put up.

This yr, efficiency in SQA exams stays just like final yr with 75 younger individuals throughout Moray reaching six ‘A’ grades at Nationwide 5.

34 younger individuals reaching seven or extra ‘A’ grades at Nationwide 5; and 163 passing (A-C), seven or extra {qualifications} at Nationwide 5.

Throughout Moray faculties, 26 younger individuals in S5 achieved 5 or extra ‘A’ grades at Increased, barely decrease than 2023 however the second highest yr of efficiency the place remaining examinations and coursework have been the principle types of evaluation.

In S4, 89% of younger individuals achieved an award (A-D) at S4 Nationwide 5 akin to final yr’s information.

In S4, 39 younger individuals achieved eight or extra {qualifications} in S4 at Nationwide 5 with 25 younger individuals reaching a number of Increased (SCQF stage 6) passes in S4.

Optimistic efficiency in S4 is famous in Administration and IT, Artwork and Design, Enterprise Administration, Drama, English, French, German, Music, Bodily Training, Hospitality (Sensible Cookery) and Spanish.

Efficiency at S5 Increased stays akin to final session with 88% of younger individuals reaching an award at (A-D).  Specifically, 61% of younger individuals achieved a number of Increased (SCQF stage 6) qualification.

This yr 26 younger individuals achieved 5 or extra Increased ‘A’ passes in 2024, barely down from 2023’s 29 pupils.

A number of excellent particular person successes are additionally famous together with 111 younger individuals reaching 5 Increased passes at grade A-C.  Younger individuals carried out properly in Artwork and Design, Drama, French, German, Graphic Communication, Historical past, Music, Bodily Training and Politics.

At S6 Superior Increased, 87% of younger individuals achieved an award (A-D) and at S6 Increased, 84% of younger individuals introduced at this stage additionally achieved an award (A-D).

As faculties lengthen their curriculum supply primarily based on the wide selection of SCQF {qualifications} and accreditation on supply, it’s famous that research at SQA stage 6 (Increased) and SQA stage 7 (Superior Increased) stays applicable for a lot of younger individuals in our faculties and their chosen onward vacation spot after faculty.  In S6 Superior Increased, optimistic efficiency is famous in Artwork and Design, Geography, Trendy Research, Music, and RMPS.

Information from the Scottish Authorities Perception benchmarking device is predicted in September and can assist consider how college students are doing in SCQF {qualifications}, particularly in ungraded programs.   Achievements can even be analysed in a wider vary of {qualifications}, together with programs that many younger individuals in Moray  are taking as a part of school Wednesday with Moray Faculty UHI.

Councillor Kathleen Robertson, Chief of Moray Council and Chair of Training, Kids’s and Leisure Providers Committee mentioned: “I need to lengthen my congratulations to all the scholars receiving their examination outcomes at present. Your achievements mirror the onerous work and perseverance you’ve proven all year long, and we’re all very pleased with you.

“The talents and experiences you’ve gained throughout your time in class will open many doorways, and we’re right here that will help you discover the best path.”

In response to this yr’s SQA examination outcomes, Vivienne Cross, Head of Training (Chief Training Officer) at Moray Council mentioned: “Congratulations to all of our younger people who find themselves receiving their outcomes this morning.  Many people have excellent outcomes nevertheless for individuals who don’t obtain what they anticipate please don’t worry.  College workers will probably be obtainable to debate choices with you and recourse if crucial.

“Along with this, we’re increasing ungraded course choices by way of SCQF {qualifications} to offer extra personalised studying paths for our college students.

“For all these Moray younger individuals transferring to a brand new pathway from faculty we want you each success within the years forward.”

Pupils in search of help or recommendation can contact their faculty within the first occasion.

Abilities Improvement Scotland are additionally readily available to help with recommendation and subsequent steps by way of the Examination Outcomes Helpline and are contactable on 0808 100 8000.

The SQA candidate recommendation line will also be reached on 0345 279 1000 or common recommendation is obtainable on their web site, www.sqa.org.uk and social media @sqanews.

Younger individuals in search of recommendation about college locations or clearing ought to contact UCAS on-line on www.ucas.com, on social media (fb.com/ucasonline; X @ucas_online) or by phone on 0371 468 0468. 

Why are Trump supporters calling Walz ‘Tampon Tim’? | News

Vice President Kamala Harris chosen Gov. Tim Walz (D-MN) as her 2024 working mate on Wednesday, and supporters of former President Donald Trump shortly labeled him with a brand new nickname: “Tampon Tim.”

So the place is that this coming from?

In 2023, Walz backed state laws that required public faculties to supply female merchandise, together with tampons, pads, and different gadgets, in all restrooms utilized by college students in grades 4 via 12.

Minnesota Republicans sought to amend the laws earlier than its passage to restrict these merchandise to solely ladies’s restrooms however have been blocked. The regulation went into impact on Jan. 1 of this 12 months.

Walz beforehand served as a member of the U.S. Home of Representatives on high of a 24-year profession as an educator and Nationwide Guardsman, and his choice by Harris was instantly heralded by progressives and LGBT rights teams. However Republicans, together with high Trump marketing campaign officers, highlighted the varsity lavatory controversy. 

Trump adviser Stephen Miller, responding to the Walz choice, posted on X, “She truly selected Tampon Tim,” shortly after the time period started trending on social media.

Trump marketing campaign spokeswoman Karoline Leavitt equally attacked Walz over the toilet regulation throughout a Wednesday night time look on Fox Information.

“As a lady, I believe there isn’t a larger risk to our well being than leaders who assist gender-transition surgical procedures for younger minors, who assist placing tampons in males’s bogs in public faculties,” she mentioned in an interview. “These are radical insurance policies that Tim Walz helps. He truly signed a invoice to do this.”

“What could possibly be weirder than signing a invoice requiring faculties to inventory tampons in boys’ bogs?” Make America Nice Once more Inc., a high tremendous PAC backing Trump’s 2024 bid, added in an announcement.

CLICK HERE TO READ MORE FROM THE WASHINGTON EXAMINER

Walz has a historical past of backing LGBT rights. As a Home member, Walz supported legalizing same-sex marriage and he backed the repeal of “Do not Ask Do not Inform” to permit homosexual members of the navy to serve brazenly. As governor, Walz signed a “trans refuge” invoice banning Minnesota from cooperating with makes an attempt to prosecute out-of-state sufferers looking for reproductive or gender-transition therapy. Walz additionally banned conversion remedy therapy for LGBT minors looking for to alter their sexual orientation or gender identification. 

The Harris marketing campaign declined to touch upon this story.

SQA results success 2024 | The Highland Council

At the moment we rejoice the success and achievements of all our younger individuals as they obtain their SQA outcomes. These outcomes are an preliminary snapshot of attainment and achievement for the 2023/24 session, with a fuller image accessible later within the 12 months when different accreditation corresponding to faculty programs and wider achievement awards are finalised. 

Younger individuals throughout the Highlands are receiving their SQA examination outcomes at present (Tuesday 6 August 2024), reaching optimistic {qualifications} with elevated Nationwide 5 entries from the earlier 12 months; 75.6% of candidates attaining A-C grades; and a rise within the variety of pupils attaining grade As.

 Headline messages in comparison with 22/23 leads to the primary, point out

  • In S4 extra younger individuals attained Nationwide 5 English and Maths award in comparison with the earlier 12 months with 68.1% attaining Nationwide 5 English and 47.9% attaining a Nationwide 5 Maths award.
  • There was improved attainment by S4 pupils from our most disadvantaged areas with a 5% improve in Nationwide 5 awards for this group of leaners.
  • In S6 there was a notable improve within the variety of pupils attaining 1 or extra Degree 6 awards. 67.6% of younger individuals in S6 attained 1 or extra degree 6 award, a rise of three.5% on the earlier 12 months.
  • Equally, in S6, there is a rise share of younger individuals attaining 3 or extra degree 6 awards with 27.7% reaching this award in comparison with 27.1% in 2023.
  • For Superior Highers the A-C cross charge was down barely on 2023 by 1.5%.
  • In S5, there was a slight decline on the earlier 12 months of younger individuals attaining 5 or extra Degree 6 awards, however remaining regular with the final three 12 months Highland common.
  • There has additionally been a dip within the proportion of S4s attaining A, B or C grade at Nationwide 5 this 12 months.

A fuller image can be accessible later within the 12 months when different accreditation corresponding to faculty programs and wider achievement awards are finalised.

Training Committee Chair, Cllr John Finlayson mentioned: “At the moment marks a big milestone for all of the pupils receiving their SQA examination outcomes, and this 12 months’s knowledge from throughout Highland displays the resilience and exhausting work of all our younger individuals and their academics. There’s a lot to rejoice throughout Highland by way of this 12 months’s outcomes, and I want to congratulate all who’ve achieved the outcomes they hoped for.

“To these younger people who find themselves disenchanted with any of their grades, please don’t overlook that there’s a substantial amount of assist accessible to you in your college that can assist you to resolve what your subsequent steps can be. For these younger individuals on this place, I’d urge you to make contact, together with your Private Help Trainer as they may have the ability to offer you recommendation, as will Abilities Growth Scotland Officers. I’d additionally urge dad and mom and carers to take time to speak over examination outcomes with their younger individuals and to rejoice and provide assist the place it’s required.

It’ll take us a little bit time to analyse the outcomes and the way these evaluate nationally.  Nonetheless, our preliminary evaluation suggests attainment in Highland largely mirrors the nationwide image. You will need to acknowledge, because the Cupboard Secretary for Training mentioned herself this morning, that is the primary 12 months since 2019 that the total vary of exterior evaluation has been undertaken, with no changes made for Covid.  On the similar time, there isn’t any doubt that the cohort of younger individuals taking exams this 12 months have skilled important disruption of their schooling during the last 4 years.  They’re to be congratulated on their exhausting work and resilience.”

Assistant Chief Government – Folks, Kate Lackie mentioned: “I want to congratulate all our younger individuals at present as they obtain accreditation for his or her achievements, for each graded and ungraded course awards. At the moment’s outcomes mirror the exhausting work of the scholars over many months and years of examine and the assist and steering of their households, academics and wider college workers.

“The place a youngster could not have acquired the grades or {qualifications} they got down to obtain, it is just pure that they are going to be disenchanted.  I’d encourage anybody on this place to entry the assist and steering that’s accessible to assist them. It is usually vital to recognise that exams are usually not the only path to success. Highland has a powerful observe report in supporting our younger individuals to attain optimistic locations in schooling, coaching and employment, and our faculties have labored exhausting with all our younger individuals in growing their expertise for studying for all times and work.”

Assist and recommendation is accessible for all college students receiving their outcomes from their very own faculties and in addition from Abilities Growth Scotland’s devoted Examination Outcomes Helpline which is accessible for every week from at present onwards to assist younger individuals.

SQA’s Candidate Recommendation Line service is freed from cost and opens at 9am on outcomes day.

Helplines

SQA Candidate Recommendation – 0345 279 1000.

Abilities Growth Scotland’s Outcomes – 0808 100 8000.

UCAS – 0371 468 0468

Extra info has been despatched to learners’ houses and is accessible at www.sqa.org.uk/outcomes.

Clearing sources could be discovered at www.ucas.com/clearing.

Olympics star Steve Cram: ‘Nothing else feels like winning a race’

I used to be turning into fairly politically conscious. There have been strikes and energy cuts, so our lives had been affected by politics. My grandfather was a miner, my coach was working within the shipyards, my mum labored at three or 4 factories – that’s what individuals did. It was a correct working-class upbringing. And I used to be formed by the place I grew up and the individuals round me. 

My mom was German and my dad was a policeman – each of these issues made you stand out in Jarrow. All my life, we’d lived in a police home. Most estates had just a few, which was good however meant everybody knew the place you lived. And we’d go to Germany yearly, which was uncommon. None of my mates had been overseas. I used to be extra conscious of what was occurring at dwelling via this lens of getting parentage from a unique nation – and theoretically a rustic we hated. I turned conscious of racism, as a result of my mum suffered fairly badly.

1982: Dad and mom Invoice and Maria showcase a few of his trophies. Picture: ANL/Shutterstock

This was the time of Until Loss of life Us Do Half and Love Thy Neighbour. So my mates would come round, say issues they’d heard at dwelling, and my mum would go ballistic. Any prejudice was frowned upon. And being a policeman’s son meant you needed to behave. If my mates have been going to do one thing even barely dodgy, my first thought was, what if my dad finds out? 

One in all my uncles [Bobby Cram] was an expert footballer. He was a hero to me, he performed for West Brom, he was in the identical staff as Bobby Robson and Jeff Astle, after which had a second of fame. He was captain of Colchester in 1972 once they knocked Leeds United out of the FA Cup reside on tv. I used to go to my grandmother on Sundays and look via scrapbooks on my uncle. I used to be not ok to comply with in his footsteps. By 15 I’d given up soccer to take operating extra significantly. 

1982: with a few of his medals. Picture: Trinity Mirror / Mirrorpix / Alamy Inventory Photograph

My careers trainer stated you’ll not earn any cash by operating and that I wanted a correct profession. Years later, Mr Harrison was working for the Northumberland Vacationer Board and he’d be on the stand at Newcastle Airport. He was a beautiful man, however each time I flew to Oslo or Zurich, I reminded him about it! To be truthful, my mum and pa have been saying the identical. The phrase they used was having ‘one thing to fall again on’.

I went to the Commonwealth Video games once I was 17 and all of the sudden my title was on the again pages of the newspapers. Soccer wasn’t taking over all of the headlines prefer it does now. And we had Seb Coe and Steve Ovett, who have been capturing the general public creativeness. I broke the world mile document for 17-year-olds and began getting consideration and sponsorship. My life modified shortly. Abruptly, A ranges didn’t really feel so vital. You’re considering calculus – what am I going to do with this?

I used to be devoted to operating however didn’t miss out on teenage life. I went to events and had a drink at times. At 16 or 17, that’s the time most children cease doing sport. You socialise extra and are occupied with ladies or boys. By 16, everybody knew which bar you possibly can get served in, in order that was arduous to withstand. And I did sufficient to not really feel like I used to be lacking out. As nice a profession as I had, boring stuff like getting extra sleep and my food plan would have helped. Damage prevention is massive in our sport now. So I might inform my 16-year-old self to get within the gymnasium. However the first time I went I used to be scared stiff – it was all sweaty blokes with weights who have been most likely taking medication.

Brendan Foster was an enormous hero and I had entry to him. He was an athlete within the Nineteen Seventies and lived down the street. Seeing somebody who regarded like me, smelled like me, talked like me was so vital. My coach Jimmy was nice, my mother and father have been very level-headed and I had good mates. However having Brendan, who had seen all of it and was nonetheless doing it, was unbelievable.  

1985: Surrounded by autograph hunters in Oslo after setting a brand new mile world document of
3 minutes 46.32 secs. Picture: Steve Powell/Getty Photos

My youthful self would have been most excited to know that he would break the world mile document. Roger Bannister was an unimaginable hero. I’d seen grainy footage of him breaking the four-minute mile and as a child, it was form of factor you examine in comics. It was an iconic second. So for those who’d informed me that at some point I’d break the world mile document that might have gotten me actually excited. And it nonetheless does at the moment. I’m very pleased with being in that small membership – I solely misplaced the British document just a few weeks in the past. 

No person tells you that for those who get actually good at athletics you’re going to turn into well-known. Instantly, in all places we went, everybody knew who we have been. After I received the World Championships in 1983 and went to the Olympics in 1984, I couldn’t stroll down the road wherever. Tv was pulling the strings. After I broke the 1,500m world document in Good in 1985, it was reside on BBC and ITV. About 20 million individuals watched it on a Tuesday evening.

So the influence of what we have been doing was enormous. Just a few weeks later I broke the mile document in Oslo and that race was at midnight as a result of we needed to be reside on TV on the West Coast of America. I began getting letters from all all over the world. It was unimaginable to be a part of and I might by no means have it every other method, however I did discover it overwhelming. 

Tv’s an exhilarating business to be concerned in and I’ve been in it quite a bit longer than I used to be a runner, however nothing else looks like profitable a race. Now and again I do not forget that feeling of coming down the house straight, figuring out you’re operating nice and can win a medal, run a private finest or set a world document. And you may’t change that. Daley Thompson used to say to me, ‘don’t cease, it’s crap exterior’.

2016: With Daley Thompson for an occasion at Royal Backyard Lodge in London in support of youngsters’s charity Coco. Picture: WENN Rights Ltd / Alamy Inventory Photograph

My supervisor sorted Brendan Foster, Des Lynam, John Motson, Jim Rosenthal and Alan Parry.  So whilst an athlete, I understood broadcasting as a result of I hung round with these guys. However for those who’d informed me I might find yourself on TV, I might by no means have believed you. I stumbled into broadcasting. I began with Eurosport and was crap at first. However it was a method to return to the World Championships and the Olympics. That was my motivation. 

To succeed in the highest degree in sport you possibly can turn into fairly egocentric. So I’d inform my youthful self to be sure to’re conscious of what’s taking place in different individuals’s lives. It’s not all about you. Know who your actual mates are and don’t be so self-obsessed.

My brother’s dying made me make some massive modifications. He tripped when he was out operating, fractured his cranium and died on the spot. He was 40. There was a giant feeling of guilt – why him? However it was additionally a jolt for me and I thank him to at the present time. You realise there would possibly solely be tomorrow, so why not be doing what you need to do and residing as you need to reside? The following couple of years I obtained divorced, and it was all a part of that interval of reassessing my life. 

After I was ending as a runner, there was an possibility for me to turn into an MP. I’m political within the sense that I need to do issues, and within the mid-Nineties I used to be very annoyed with what was taking place in sport. Seb Coe had turn into an MP, which took me aback. I’d had political discussions with all my mates within the Nineteen Eighties, however by no means him. I informed him I wished to do it as a result of sport in faculties was horrible. However he stated influential sports activities individuals can sit in entrance of a politician and discuss points greater than a backbench MP. And he was proper. I sat on the Lottery panel for 15 years – that course of ended with us having the Olympics in 2012. So Seb was shrewd and stopped me taking place a path which will have been a lifeless finish. However I like speaking politics. 

The scariest factor of my life was when somebody stated I used to be going to switch David Coleman. It’s like the sensation Prince Charles may need had earlier than he turned king. How do I comply with that? He was the best sports activities broadcaster and was in all places in my home once I was a child. And he commented on my nice moments. Athletes now solely know me as a commentator.

After we are masking the Olympics, there’s at all times a subtext: perhaps our subsequent champions are watching. There might be eight or 9 12 months olds who will watch Mondo Duplantis and suppose, wow, the pole vault seems to be enjoyable. Or perhaps in ten years time somebody might be in a press convention, remembering how, once they have been a child, they watched Keely Hodgkinson win the 800m in Paris. And that’s the reason it’s so vital that the BBC has a platform to indicate the Olympics.

We’re in one other operating increase and I like it. The primary London Marathon in 1981 was on the BBC and satisfied lots of people to take up operating. A lady known as Madge Sharples, who was 64, was on and folks at dwelling have been going, if she will do it, so can I. Our firm Occasions Of The North organises occasions now and I like seeing individuals who would by no means have contemplated doing a 5k or a 10k in my day. I’m additionally a coach on Sofa to 5k, which is an app the BBC and NHS run and has been an incredible driver of individuals taking their first steps. I genuinely love all of it. As a result of once I was a child, you’d get laughed at operating across the streets of South Tyneside. There have been estates you didn’t dare run via since you’d get shouted at or stones thrown at you. Now you possibly can’t transfer for runners and I feel that’s sensible.

Steve Cram is commentating for the BBC on the Olympics in Paris

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Angelman syndrome treatment ION582 eases symptoms: Trial data

Ionis Prescription drugs’ investigational Angelman syndrome therapy ION582 demonstrated a positive security profile and lessened total signs in sufferers taking part within the HALOS medical trial.

That’s in keeping with six-month follow-up knowledge from half one in every of Section 1/2 examine (NCT05127226), which examined three doses of ION582 — low, medium and excessive — injected immediately into the spinal canal for 3 months.

Total and clinically significant enhancements have been noticed in 97% of sufferers given medium and excessive doses of ION582, as assessed by the Signs of Angelman Syndrome-Clinician International Impression of Change (SAS-CGI-C) scale, which measures clinicians’ impressions of Angelman signs, in keeping with a firm press launch.  Enhancements in communication, cognition and motor expertise have been additionally reported, and the investigational remedy was deemed secure and nicely tolerated throughout all examined doses.

Ionis stated it expects to launch a pivotal Section 3 examine to proceed to check ION582 in Angelman sufferers within the first half of 2025. The corporate will talk about trial design with regulators later this yr.

Advisable Studying

Outcomes place Angelman syndrome therapy as ‘cornerstone’

“Ionis appears to be like ahead to collaborating with investigators, regulators and members of the Angelman syndrome neighborhood to provoke Section 3 growth for ION582 within the first half of 2025,” stated Brett Monia, PhD, Ionis CEO. The “encouraging outcomes” from the trial “place ION582 to be the cornerstone of Ionis’ subsequent wave of transformational, wholly owned medicines for neurological situations, which at present contains 5 clinical-stage applications,” Monia stated.

Angelman syndrome is brought on by mutations within the maternal copy of the UBE3A gene, which prevents a working model of the UBE3A protein from being made. Whereas two copies of every gene are inherited — one from every organic father or mother — in sure areas of the mind, solely the UBE3A copy inherited from the mom is lively.

ION582 was designed to activate the paternal copy of the UBE3A gene by blocking a molecule, Ubiquitin Protein Ligase E3A-Antisense Transcript, that silences it.

The open-label HALOS medical trial enrolled 51 sufferers, ages 2 to 50. With the completion of the primary half, eligible sufferers will now transition to the second a part of the examine, which can consider the consequences of the medium and excessive doses of ION582 for a further 12 months. Within the third half, sufferers will probably be adopted for extra 4 years.

The trial’s predominant purpose is to evaluate the protection and tolerability of a number of ascending doses of ION582.

Exploratory efficacy parameters embody modifications in sufferers’ communication, cognition, motor perform, sleep, seizures, and every day dwelling expertise. These results have been measured utilizing the SAS-CGI-C and the Bayley-4, additionally a clinician-administered evaluation of medical functioning.

Advisable Studying

Enhancements seen throughout affected person inhabitants

Father or mother-reported evaluations have been performed utilizing the Vineland Adaptive Conduct Scales-3 (Vineland-3) and the Observer-Reported Communication Capability (ORCA), which assesses the standard of nonverbal communication by mother and father or caregivers.

Sufferers exhibited enhancements in communication, cognition, and motor perform in comparison with the pure growth delay seen in pure historical past research of Angelman syndrome. Wonderful motor expertise (handwriting and greedy, for instance) improved in 72% of the sufferers, cognition in 67%, and expressive communication in 69% when assessed utilizing the Bayley-4.

In accordance with ORCA, 60% of sufferers confirmed enhancements in nonverbal communication. Receptive communication expertise within the Vineland-3 improved in 89% of individuals and expressive communication in 84%. Socialization expertise have been improved in 63% to 87% of the sufferers, and every day dwelling expertise in 74% to 82%. Wonderful motor expertise improved in 63%, and gross motor expertise (equivalent to strolling and climbing stairs) in 53%.

When measured utilizing the SAS-CGI-C scale, cognition improved in 85% of sufferers. Sleep improved in 61%, and habits in 56%. These enhancements have been seen in a “broad affected person inhabitants,” Ionis stated.

“Angelman syndrome is a severe neurodevelopmental dysfunction with life-long impairments and dependence on caregivers, for which we at present have solely supportive care,” stated Lynne Hen, MD, professor of medical pediatrics on the College of California San Diego and an investigator on the HALOS examine. “We’re very inspired by these promising knowledge with ION582, displaying constant enhancements over what we observe within the pure course of the illness.”

Detailed outcomes of the HALOS medical trial have been shared on the 2024 Angelman Syndrome Basis Household Convention, which passed off July 23-26 in Sandusky, Ohio.

ION582 was granted orphan drug and uncommon pediatric illness standing by the U.S. Meals and Drug Administration (FDA), two designations aimed toward supporting and assist pace its growth.

Her Mental Health, Sleep Routine

Gabby Thomas is without doubt one of the quickest folks on the 2024 Paris Olympics and on this planet. The U.S. runner gained a gold medal within the girls’s 200-meter race ultimate on Tuesday, Aug. 6.

“You put together for this second and prepare so onerous for this second, however when it really comes, it’s indescribable,” Thomas mentioned after her decisive victory.

It took her simply 21.83 seconds to cowl the space and end in first place.

Gabby Thomas celebrates successful the gold medal after competing within the girls’s 200-meter ultimate on the Paris Olympics on August 6, 2024.Michael Steele / Getty Pictures

She calls sprinting her “pleased place.”

“I really feel so pleased operating after I see the end line in my sights, I simply have that enhance that I do know I can get there, stretch my legs out and go,” Thomas informed NBC after the 200-meter semifinals on Aug. 5.

The 27-year-old athlete beforehand competed within the Tokyo Olympic Video games, successful a bronze medal within the girls’s 200-meter and silver within the girls’s 4×100 meter relay.

Thomas can also be spectacular off the observe. She holds a bachelor’s diploma in neurobiology from Harvard College and a grasp’s diploma in public well being from the College of Texas Well being Science Heart.

After coaching three-to-six hours a day, Thomas volunteers at a clinic in Austin, Texas, for individuals who haven’t got medical insurance. She leads a hypertension program there and informed NBC Information she in the end desires of operating a hospital or a nonprofit to increase entry to healthcare.

Right here’s what to know in regards to the observe and area star, and her well being:

She calms herself down earlier than operating

TODAY’s Hoda Kotb marveled at how calm Thomas appeared when she arrived in Paris because the heavy favourite to win the 200-meter race.

“I knew coming into this that it was going to be an immense quantity of strain and simply a lot weight on my shoulders in a means that I would by no means skilled earlier than,” Thomas mentioned in a phase that aired on Aug. 7.

“I noticed I used to be going to must compartmentalize that.”

She did it by preserving issues gentle, joking round with the opposite rivals and “not making the second too heavy” — till it was time to arrange for the race within the beginning blocks.

Whereas different runners may flip to high-tempo music for a lift of vitality earlier than they compete, Thomas doesn’t hearken to her “pump-up playlist” in any respect earlier than her race.

“I wish to be so Zen, I wish to be so relaxed, and I wish to protect my vitality,” she informed NBC’s Savannah Sellers.

“After which the cut up second when the gun goes off, that’s after I wish to really feel that pump-up vitality.”

To keep away from being distracted by her rivals or the group, she picks a degree on the observe and simply concentrates on sprinting towards it. “It’s essential have a spotlight if you’re in that second,” she says.

She loves the push of operating

Thomas is taken into account a late bloomer to the game. She initially performed softball and soccer as a teen, and ran in highschool, however it wasn’t till her time at Harvard that she began turning into a standout athlete in observe.

“It’s very easy to fall in love with operating,” Thomas informed USA Immediately. “It may be painful at occasions, however it’s such a stupendous sport. You set objectives and go after them within the purest type — and if you obtain these objectives, it’s such an addicting feeling.”

Profitable the gold medal took plenty of years and plenty of persistence, she mentioned on TODAY, thanking everybody who helped her alongside the way in which.

“I do not suppose I’ve ever labored so onerous for something in my life,” Thomas added. “All of it got here collectively for this second.”

She prioritizes sleep

“As you mature as an athlete, you understand simply how vital sleep is,” Thomas informed The Washington Publish. “Not simply to be an elite athlete, however simply to be a practical human.”

She now will get a minimum of eight hours of sleep an evening.

Ample sleep is vital for peak athletic efficiency, the Worldwide Olympic Committee famous in a 2019 assertion addressing  psychological well being in elite athletes.

All wholesome adults — whether or not they’re competing within the Olympics or not — have to sleep a minimum of seven hours an evening for optimum well being, the American Academy of Sleep Drugs advises.

She takes care of her psychological well being

The athlete makes time for restoration and relaxation, and follows her passions apart from operating.

“The best way I turned profitable in observe and area was principally operating observe half time, and I believe for me, that’s actually vital for my psychological well being,” Thomas informed NBC’s Kate Snow. “Simply having different issues in my life that assist fulfill my objectives and make me really feel fulfilled.”

That features volunteering on the Austin clinic, the place she likes understanding she’s making a distinction in folks’s lives.

Thomas additionally spends time along with her canine, a pug named Rico. The athlete says she will get plenty of emotional help from her furry companion.

When issues “aren’t going tremendous nicely, it’s straightforward to really feel like I’m a failure. As a substitute of sitting in that, I bought a buddy. Adopting Rico is the most effective factor I ever did,” Thomas informed Ladies’s Working.

She enjoys low-impact train

The sprinter makes room for Pilates in her routine, embracing the way in which her physique shakes throughout the intense core exercise. She describes it as “actually onerous,” but in addition stress-free.

“Pilates is humbling,” Thomas informed Ladies’s Well being. “As an Olympian in that room, not having the ability to do plenty of the workouts that they’re doing, you actually understand what number of small muscle mass that you just don’t activate daily.”

Pilates may be completed on a mat or on a reformer machine. When TODAY’s Craig Melvin tried the reformer model, he referred to as it “maybe essentially the most intense train” he’d ever completed.

Gabby Thomas peak

The sprinter is 5 toes, 10 inches tall, in response to her official Olympic profile.

What number of siblings does Gabby Thomas have?

She has a twin brother, Andrew, and three youthful siblings — Desi, Tyler and Kim, in response to her Olympic profile.

Peacock is streaming the Paris Olympics across the clock. Be taught extra about accounts right here. TODAY earns a fee on purchases. Peacock is owned by our dad or mum firm NBCUniversal.

What to know, when to watch – NBC New York

Crew USA’s Gabby Thomas is about to compete for gold within the 200m ultimate on Tuesday on the Paris Olympics after successful bronze within the occasion in Tokyo.

Thomas is the favourite to win gold after having the highest time of 21.86 within the semifinals. She additionally had the highest time of 21.81 within the U.S. Olympic Crew Trials in June. Thomas received the 200m bronze medal within the 2020 Tokyo Olympics.

The 200m ultimate will happen on Tuesday, Aug. 6 at 3:40 p.m. ET from the Stade de France.

The U.S.’ Brittany Brown and McKenzie Lengthy may even be racing within the 200m occasion ultimate.

Thomas’ private greatest within the 200m is 21.60 seconds and her season greatest is 21.78.

The world and Olympic report within the occasion by set by the USA’s Florence Griffith-Joyner in Seoul in 1988.

When is the ladies’s 200m ultimate?

The 200m ultimate will happen on Tuesday, Aug. 6 at 3:40 p.m. ET from the Stade de France.

Methods to watch the ladies’s 200m ultimate?

The ladies’s 200m ultimate will probably be proven reside on NBC and Peacock. It should additionally stream reside at NBCOlympics.com on the hyperlink right here.

Gabby Thomas soared to victory within the girls’s 200m ultimate with a time of 21.81 seconds to ebook her spot in Paris, her second Olympic Video games.

The place is Gabby Thomas from?

Gabby Thomas was born in Atlanta however grew up in Northampton, Mass. when his mom accepted a job on the College of Massachusetts.

The place did Gabby Thomas go to school?

Gabby Thomas was recruited by recruited to go to Harvard College in Cambridge, Mass. the place he received the 2018 NCAA Indoor title within the 200m.

Community rallies together to bring beloved Macaw back to his home | Human Interest






A Macaw was capable of miraculously be returned to his house owners just lately after a scary ordeal the place the hen flew away from his residence.

‘Hoggle’ is a Schriever-based Macaw that has been owned by Ronny and Dana Friloux for actually his complete life. He hatched, was given to the Friloux’s and so they had the hen since he was 1 day outdated.

The hen flew away from his cage and was gone for a number of days earlier than he was lastly capable of be rescued and brought again residence. 

Dana Friloux shared Hoggle’s wonderful story to The Gazette this week, saying that she is so grateful to the neighborhood for his or her assist. The Friloux’s shared their story on social media because it occurred, and a military shaped in assist of Hoggle and bringing him again residence. 

“I’m so grateful for everybody,” she stated. “We are able to’t say thanks sufficient to everybody.”







 

For the Friloux’s, being a ‘hen mother’ is one thing they cherish.

The household loves Hoggle like a son. They acquired him as a day-old simply hatched out of his egg. They nurtured and hand-fed Hoggle as a child when he was bald and had no feathers and so they watched him develop to grow to be the gorgeous, colourful tropical hen that he’s right now. 

“He was ugly,” Dana says with fun remembering Hoggle as a child. “He was my tropical hen.” 

The Friloux’s lived in South Lafourche after they acquired Hoggle, however they moved to Schriever after Ida. When there, they acquired the hen a giant outside cage. 

Dana stated she put Hoggle out to get just a little solar and outside time when issues took a flip.

Simply earlier than darkish when it was time for the hen to return in, Dana opened the cage, and Hoggle grew too huge for his britches. He flapped his wings, caught air and flew away — right into a tree two tons away. 

The household tried to get Hoggle down, however couldn’t. He slept within the tree for the evening. 

The subsequent morning, a nervous and anxious Dana went exterior and referred to as for her beloved Hoggle.

“He answered,” she stated. 

Dana stated she perked up understanding Hoggle survived the evening, however the pleasure was short-lived as a result of he didn’t come down. 

When she walked residence, the hen made a break, flying above Dana’s head and in a circle over his proprietor’s head. He then flew into one other tree about 7 homes down. 

Whereas the Friloux’s tried to get Hoggle out of the tree, the hen confirmed his character. He talked, sung and pruned himself, however didn’t transfer.

When Dana’s daughter, Demi drove as much as assist try to get the hen out of the tree, Hoggle acquired excited and danced and talked to his sister, however once more — he didn’t transfer.

He did transfer out of the tree later that day, however moved to a tree even greater — farther from his mother and pa who nervous if he’d ever come residence. 

The subsequent morning, the Friloux’s once more referred to as out to Hoggle, however he was not there, which led Dana to suppose the worst. 

“I used to be devastated,” she stated, “I cried. He’s like my son. We raised him. We needed to hand-feed him each 4 hours similar to a child. It takes so much to be hen mother and father. That’s not a straightforward animal like a canine or a cat.” 

However whereas Dana laid on the couch and cried, she acquired the telephone name she is going to always remember.

A pal searching for Hoggle discovered him and he was of their tree. 







So the method began once more. Dana and Ronny went to the tree in the midst of the day within the beating summer season solar and pleaded with their beloved pet hen to fly right down to them and are available residence.

Hoggle wasn’t simply being cussed. Macaws instinctively fly as excessive as they’ll when within the wild and so they instinctively don’t land on the bottom as a protection mechanism.

Dana stated she’d take a look at the hen and he would edge towards flying off the department, however he couldn’t carry himself to bypass hundreds of years of evolution and go towards his instincts — regardless of now being hungry and thirsty. 

“He can be so scared and confused,” she stated. 

However by this time, Hoggle had developed a military along with his mom sharing updates on social media and the neighborhood getting behind returning the hen residence. 

Dana stated a member of the family was going to hire a man-lift to assist in the search, and whereas that was in course of, the Schriever Hearth Division confirmed as much as assist out. 

Together with his mother on an extension ladder, Dana made one other plea to Hoggle to return down. He tried, however once more couldn’t — too fearful to maneuver.

However the Schriever Hearth Division then acquired inventive. Firefighters requested Dana for permission to spray the hen with a hose of water in an try and make the hen transfer out of the tree and are available to the bottom.

It took a number of sprays and a number of tries, however lastly, Hoggle fell to the bottom, and Dana ran via a “boo-poo-dee” ditch to find, seize and hug her son. 

“I used to be so relieved,” she stated. “Hoggle was lastly residence.” 

The hen was exhausted when he acquired residence. He was dehydrated and hungry. He ate, drank and stayed on the bottom in his cage for some time — as a option to keep cool. 

In the present day, Hoggle is again to his regular self, and is singing and speaking up a storm to those that go to him.

Dana stated Hoggle shouldn’t be allowed exterior anymore — at the least not till he will get his wings clipped within the coming weeks. Then, he’ll get again out in his outside cage and luxuriate in some recent air.

“You’d suppose nothing ever occurred to him,” she stated with fun. “We’re so grateful to have him again and we thank everybody — our mates, our household, our neighbors, the Schriever Hearth Division and all of our social media mates for his or her assist in bringing him again residence.”

This FTSE 250 bargain down 45% gives me a breath-taking 9% yield

Picture supply: Getty Photographs

I’ve been scouring the FTSE 250 for dirt-cheap dividend shares with ultra-high yields and it didn’t take me lengthy to seek out one.

Asset supervisor abrdn (LSE: ABDN) has had a depressing run since being fashioned by the £11bn merger between fund managers Customary Life and Aberdeen Asset Administration in March 2017. As we speak, the group is price a meagre £2.87bn. 

The merger failed on each entrance because the group needed to cull greater than 100 funds that principally did the identical job, blundered right into a authorized battle with Lloyds, which pulled £25bn of its fund mandate, and have become a comedy meme after its much-lampooned 2021 rebrand. Now I believe the sell-off has been overdone (or ovrdn, because the abrdn may say).

abrdn is due a cmbck

The abrdn share worth is down 27.22% over 12 months and 43.45% over 5 years. These numbers counsel there’s deep worth right here, together with a surprising dividend earnings yield that’s now a breath-taking 9.01%.

The shares look good worth at simply 11.35 occasions trailing earnings. That’s barely beneath the typical FTSE 250 P/E of 12.2 occasions.

In at present’s half-year outcomes, interim CEO Jason Windsor reported an “encouraging begin” to 2024, “as we turn into extra environment friendly, and we improve our propositions to put the foundations for development”.

Observe he mentioned “lay” the foundations. The expansion isn’t truly there but. Web working income truly fell 7% to £667m as a result of outflows and decrease margins, partly offset by improve in adviser income.

Adjusted working revenue climbed 1% to £128, largely by a 9% reduce in adjusted working bills to £539m. abrdn is on monitor to save lots of £150m a 12 months by the tip of 2025.

Tough sector

Belongings underneath administration climbed 2% to £505.9bn as a result of optimistic market actions and flows. On an IFRS foundation, final 12 months’s £169m loss swung to a £187m revenue earlier than tax.

The abrdn share worth jumped nearly 5% in early buying and selling, earlier than rapidly sliding again. It’s nonetheless low cost, after that flurry of pleasure, however one factor worries me.

I not too long ago checked FTSE 100-listed family-owned fund supervisor Schroders and it’s been going by a equally rocky time. Its shares have crashed 24.12% in a 12 months and 46.6% over three years. The inventory at present trades at 13.64 occasions earnings whereas yielding 6.4% a 12 months.

A number of FTSE 100 financials are in an identical place. Wealth supervisor M&G and asset supervisor Authorized & Basic Group instantly spring to thoughts. Each supply bumper yields whereas their shares battle to make headway. Now right here’s the factor. I maintain each in my self-invested private pension (SIPP).

I believe the asset administration sector is due a rerating, but it surely’s taking longer than I’d initially hoped. Given my publicity, I don’t want so as to add one other high-yielding struggler to my SIPP. There’s a possibility right here, however I’m already chasing it. With remorse, I’ll look elsewhere for my high-yield FTSE 250 restoration play. A lot to select from proper now!